आक्रन्दाट्ठञ्च

Operational rule vidhi

The affixes ठञ् and ठक् come after the word आक्रन्द being in the Accusative -2nd case in construction in the sense of 'who runs'.

Word by word (padaccheda)

Left context आक्रन्दात् pañcamī · ekavacanaSubstitute / term prathamā · ekavacanaIndeclinable च avyaya

Left context Pañcamī (5th case): "after X", the operation applies to what follows (1.1.67 तस्मादित्युत्तरस्य). Also used for limits and sources.
Substitute / term Prathamā (1st case): in operational rules, the substitute or the thing introduced; in definitions, the term or its referent.
Indeclinable An avyaya such as च "and", वा "optionally", न "not".

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Full reading

आक्रन्दात् ठञ् च

Pāṇini leaves out words that carry over from earlier sūtras. Expand to see the rule as a reader actually understands it.

Commentary

The affixes ठञ् and ठक् come after the word आक्रन्द being in the Accusative -2nd case in construction in the sense of 'who runs'.
The word आक्रन्द means 'a place where persons weep' e.g. a battle - field. It also means 'weeping' 'invoking' &c. The difference between ठक् and ठञ् in the accent. Thus आक्रन्दं धावति = आक्रन्दिकः꣡ or आ꣡क्रन्दिकः, f. आक्रन्दिकी 'a person who runs to a place where cries of distress are heard'.

Śrīśa Chandra Vasu, The Ashtadhyayi of Panini (1897), via ashtadhyayi.com.