अदिप्रभृतिभ्यः शपः

Operational rule vidhi

After the verb अद् 'to eat' and the rest there is लुक् elision of the विकरण शप् -- कर्तरि शप् (3.1.68).

Word by word (padaccheda)

Left context अदि- प्रभृतिभ्यः pañcamī · bahuvacanaTarget शपः ṣaṣṭhī · ekavacana

Left context Pañcamī (5th case): "after X", the operation applies to what follows (1.1.67 तस्मादित्युत्तरस्य). Also used for limits and sources.
Target Ṣaṣṭhī (6th case): names what gets replaced, "in place of X" (1.1.49 षष्ठी स्थानेयोगा).

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Full reading

अदि-प्रभृतिभ्यः शपः

Pāṇini leaves out words that carry over from earlier sūtras. Expand to see the rule as a reader actually understands it.

Commentary

After the verb अद् 'to eat' and the rest there is लुक् elision of the विकरण शप् -- कर्तरि शप् 3.1.68.
Thus अद् + शप् + ति = अत्ति 'he eats'; हन्ति 'he kills;' द्वेष्टि 'he envies.' The Adadi verbs belong to the second conjugation. In this class of verbs, therefore, the terminations are added direct to the root.

Śrīśa Chandra Vasu, The Ashtadhyayi of Panini (1897), via ashtadhyayi.com.