राधो हिंसायाम्

Operational rule vidhi

Word by word (padaccheda)

Target राधः ṣaṣṭhī · ekavacanaRight context हिंसायाम् saptamī · ekavacana

Target Ṣaṣṭhī (6th case): names what gets replaced, "in place of X" (1.1.49 षष्ठी स्थानेयोगा).
Right context Saptamī (7th case): "when X follows", the operation applies to what precedes (1.1.66 तस्मिन्निति निर्दिष्टे पूर्वस्य). Also a condition or domain ("in the sense of").

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Full reading

राधः हिंसायाम्

Pāṇini leaves out words that carry over from earlier sūtras. Expand to see the rule as a reader actually understands it.

Commentary

ए is substituted for आ of राध when meaning 'to hurt someone' and the reduplicate is elided before the affixes क् (or ङ्) or as well as before थल् of the लिट् (Perfect Tense) having the augment इट्।
Thus अपरेधतुः, अपरेधुः, अपरेधिथ, but रराधतुः, रराधुः, रराधिथ in any other sense than that of 'hurting'. In this sutra the long आ of राध is to be replaced by ए, the anuvritti of short अ (अतः 6.4.120) is therefore not appropriate here. We should either read the anuvritti of आ from 6.4.112, or we should read the word एकहलमध्ये in this way "in राध् whatever stands between two simple consonants is replaced by ए".

Śrīśa Chandra Vasu, The Ashtadhyayi of Panini (1897), via ashtadhyayi.com.