अनन्तावसथेतिहभेषजाञ्ञ्यः

Operational rule vidhi

The affix ञ्य comes without changing sense, after the words 1. अनन्ता 2. आवसथ 3. इतिह and 4. भेषजा.

Word by word (padaccheda)

Left context अनन्त- आवसथ- इतिह- भेषजात् pañcamī · ekavacanaSubstitute / term ञ्यः prathamā · ekavacana

Left context Pañcamī (5th case): "after X", the operation applies to what follows (1.1.67 तस्मादित्युत्तरस्य). Also used for limits and sources.
Substitute / term Prathamā (1st case): in operational rules, the substitute or the thing introduced; in definitions, the term or its referent.

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Full reading

अनन्त-आवसथ-इतिह-भेषजात् ञ्यः

Pāṇini leaves out words that carry over from earlier sūtras. Expand to see the rule as a reader actually understands it.

Commentary

The affix ञ्य comes without changing sense, after the words 1. अनन्ता 2. आवसथ 3. इतिह and 4. भेषजा।
Thus आनन्त्यम् = अनन्तः, आवसथ्यम् = आवसथः 'dwelling place, a sanctuary for sacred fire'. ऐतिह्यम् = इति ह 'traditional account', the affix here is added to a word which is not a pratipadika. The word इति ह means tradition, as इति ह स्मोपाध्यायाः कथयन्ति ॥ भैषज्यम् = भैषजम् ॥

It is optional to add this affix, owing to the general optional nature of all taddhita affixes. See 4.1.82.

Śrīśa Chandra Vasu, The Ashtadhyayi of Panini (1897), via ashtadhyayi.com.