सिकताशर्कराभ्यां च

Operational rule vidhi

The affix अण् comes in the sense of मतुप् after सिकता and शर्करा.

Word by word (padaccheda)

Left context सिकताशर्कराभ्याम् pañcamī · dvivacanaIndeclinable च avyaya

Left context Pañcamī (5th case): "after X", the operation applies to what follows (1.1.67 तस्मादित्युत्तरस्य). Also used for limits and sources.
Indeclinable An avyaya such as च "and", वा "optionally", न "not".

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Full reading

सिकताशर्कराभ्याम् च

Pāṇini leaves out words that carry over from earlier sūtras. Expand to see the rule as a reader actually understands it.

Commentary

The affix अण् comes in the sense of मतुप् after सिकता and शर्करा।
Thus सैकटो घटः, शार्करं मधु ॥ These are the examples, when they do not denote a place. In denoting a place they will take इल् and लुप् of the next sutra.

Śrīśa Chandra Vasu, The Ashtadhyayi of Panini (1897), via ashtadhyayi.com.